Pertuzumab (Perjeta®)

Assessment Status Assessment Process Complete
HTA ID -
Drug Pertuzumab
Brand Perjeta®
Indication The proposed licensed indication is for use (in combination with trastuzumab and docetaxel) in adult patients with HER2-positive metastatic or locally recurrent unresectable breast cancer, who have not received previous anti-HER2 therapy or chemotherapy for their metastatic disease. 
Assessment Process
Rapid review commissioned 14/01/2013
Rapid review completed 31/01/2013
Rapid review outcome Full Pharmacoeconomic Evaluation Recommended
Full submission received from Applicant 02/05/2013
NCPE assessment completed 28/08/2013
NCPE assessment outcome Reimbursement not recommended

Technical Summary

The NCPE believes that pertuzumab in combination with trastuzumab and docetaxel is not a cost-effective treatment for adults with HER2-positive metastatic or locally recurrent unresectable breast cancer who have not received previous anti-HER2 therapy or chemotherapy.