Pembrolizumab (Keytruda®) 1L squamous NSCLC with chemotherapy

Assessment Status Rapid Review Complete
HTA ID -
Drug Pembrolizumab
Brand Keytruda®
Indication In combination with carboplatin and either paclitaxel or nab-paclitaxel for the treatment of the first-line treatment of metastatic squamous non-small cell lung carcinoma.
Assessment Process
Rapid review commissioned 25/02/2019
Rapid review completed 25/03/2019
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of pembrolizumab in combination with carboplatin and either paclitaxel or nab-P compared with the current standard of care, on the basis of the proposed price relative to currently available therapies.

The HSE has approved reimbursement following confidential price negotiations – February 2021.